C-peptide reserve in insulin-dependent diabetes

Dental damages in non-insulin dependent diabetes patients

Introduction: Changes in saliva and its biochemical content in diabetic patients can effect on supportive dental tissues and cause dental damage. Low carbohydrate diets, and good control of disease can reduce dental damage in diabetics. The aim of this study was to compare dental damage in patients with non-insulin dependent diabetes mellitus (NIDDM) patients and healthy individuals. Methods: ...

Pathological consequences of C-peptide deficiency in insulin-dependent diabetes mellitus.

Diabetes is associated with several complications such as retinopathy, nephropathy, neuropathy and cardiovascular diseases. Currently, insulin is the main used medication for management of insulin-dependent diabetes mellitus (type-1 diabetes). In this metabolic syndrome, in addition to decrease of endogenous insulin, the plasma level of connecting peptide (C-peptide) is also reduced due to beta...

Biological activity of C-peptide on the skin microcirculation in patients with insulin-dependent diabetes mellitus.

19 insulin-dependent diabetes mellitus (IDDM) patients participated in a randomized double-blind crossover investigation to investigate the impact of human C-peptide on skin microvascular blood flow. The investigation was also carried out with 10 healthy volunteers. Blood pressure, heart rate, blood sugar, and C-peptide levels were monitored during a 60-min intravenous infusion period of C-pept...

High 24-Hour Urinary C-Peptide Excretion in Non-Insulin Dependent Diabetes Mellitus*

Insulin effect on Leptin Concentration in Children with New Onset Insulin Dependent Diabetes Mellitus

Objective: Serum Leptin concentration reflects the body fat mass. There is controversial reports about the insulin effect on serum Leptin concentration. We wanted to examine the effect of insulin therapy on serum Leptin in children with new onset type I diabetes. Materials and Methods: This was a Cross-Sectional study in Children's Medical Center on 34 children who had new onset type I diabe...